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Genetic variation, resistance to acaricides and immunological cross-reactivity in ticks that infest cattle in Zimbabwe and Australia

Project ID

AS2/1990/047

Inactive project countries

Zimbabwe

Commissioned Organisation

University of Queensland, Dept of Parasitology, Australia

Project Leader

Dr Stephen Barker

Email

s.barker@mailbox.uq.edu.au

Phone: 

Tel: 07 3365 2572

Fax: 

Fax: 07 3365 1588 (St Lucia)

Collaborating Institutions

Veterinary Research Laboratory, Zimbabwe

Project Budget

$890,438.00

Start Date

01/07/1993

Finish Date

30/06/1996

Extension Start Date

01/07/1996

Extension Finish Date

30/06/1999

ACIAR Research Program Manager

Dr Denis Hoffmann

Overview Objectives

One of the main problems of resistance to pesticides is that there is no satisfactory fast method to determine when resistance has built up. Currently available tests can have a 6-week lag rendering them of little use in resistance management programs. One of the main objectives of this project is therefore to identify a genetic marker(s) for resistance to organophosphate acaricides. This will then be used to develop a diagnostic kit for use in the field to identify organophosphate resistance in ticks.

Project Background and Objectives

Ticks and the pathogens they carry seriously impair cattle production in both Africa and Australia. Farmers control ticks with specially developed chemical pesticides (acaricides) but many populations of ticks have now developed resistance to them. In addition, the acaricides themselves may be toxic to livestock especially at the higher concentrations needed to overcome resistance.

A range of chemicals have been used as acaricides (e.g. organochlorine and organophosphate pesticides) and, as well as being costly to apply, these chemicals can also contaminate the environment and water supply (through cattle dips) and pose a health threat to livestock handlers. The need for new strategies to control ticks and tick-borne disease is therefore urgent.

Location

There are no project locations defined for this project.